Screening for prostate cancer typically begins at age 50, but men with a family history or higher risk should start at 40–45. It usually involves a PSA blood test and a digital rectal exam. The frequency of screening depends on PSA levels—some may need annual checks, others every two years. Regular screening helps detect prostate cancer early, improving the chances of successful prostate cancer treatment. Talk to your doctor to create a screening plan that suits your health needs.